Pressure BioSciences, Inc. has designed their products based on the properties of constant and alternating hydrostatic pressure. The result is the patented pressure cycling technology, which is also known as PCT. It is a platform that the company has patented and uses to cycle ambient to ultra-high hydrostatic pressure. This can be helpful in controlling bio-molecular interactions and temperature while maintaining a safe working environment. PCT is used on RNA, DNA, proteins, small molecules and lipid, just to name a few. Pressure cycling can also be utilized to improve and hasten the proteolytic digestion with common enzymes such as Lys-C, trypsin, and proteinase K. The main focus of their development and sales efforts are in areas of drug discovery and design, biomarker discovery, and forensics. Their customers use products in other sectors that include plant and soil biology, counter-bioterror applications, vaccine development, and bio-therapeutics characterizations.
Medical Technology Developed by Pressure BioSciences
Pressure BioSciences, Inc. develops pressure cycling technology (PCT) solutions in the United States. Its PCT technology uses alternating cycles of hydrostatic pressure between ambient and ultra-high levels to control the actions of molecules in biological samples, such as cells and tissues from human, animal, plant, and microbial sources. The company offers Barocycler instrumentations, including Barocycler NEP3229, Barocycler NEP2320, Barocycler HUB440, PCT MicroTube Adapter Kit, The Shredder SG3, Barocycler HUB880, Barozyme HT48, BaroFlex 8-well Processing Strips, and PCT-HD laboratory instrumentation. It also distributes Constant Systems cell disruption equipment, parts, and consumables. In addition, the company offers Barocycler consumable products, such as PULSE Tubes, which transmit the power of PCT from the Barocycler instrument to the sample; Non-Disk PULSE Tubes that offer variable sample volumes; and ProteoSolve for Systems Biology, which is a PCT-dependent method for the extraction, isolation, and fractionation of nucleic acids, proteins, and lipids from animal and plant samples used in laboratory research. Its Baracycler consumable products also include ProteoSolve for Conventional Extraction that is a PCT-dependent kit for the extraction of proteins from various samples; mitochondria isolation kits that contain the chemical ingredients required for a scientist to extract mitochondria from skeletal muscle and lung tissue for subsequent analysis; and PCT Micro-Pestle and PCT MicroTubes to enhance the extraction of protein, DNA, RNA, and small molecules from small amounts of solid samples, such as soft animal tissues or biopsies. Pressure BioSciences, Inc. serves researchers at academic laboratories; government agencies; and biotechnology, pharmaceutical, and other life sciences institutions. The company was formerly known as Boston Biomedica, Inc. Pressure BioSciences, Inc. was founded in 1978 and is based in
When the company was founded in Massachusetts, it was known as Boston Biomedica, Inc. While it was founded in August of 1978, its significant operations started in January of 1986. In September of 2004, most of the company’s assets and liabilities were sold, and soon after its name was changed to Pressure BioSciences, Inc. Its Initial Public Offering was in October 1996, under its former name, Biomedica.
Products Offered by Pressure BioSciences, Inc.
Pressure BioSciences, Inc. has designed their products based on the properties of constant and alternating hydrostatic pressure. The result is the patented pressure cycling technology, which is also known as PCT. It is a platform that the company has patented users to cycle ambient to ultra-high hydrostatic pressure. This can be helpful in controlling bio-molecular interactions and temperature while maintaining a safe working environment. PCT is used on RNA, DNA, proteins, small molecules and lipid, just to name a few. Pressure cycling can also be utilized to improve and hasten the proteolytic digestion with common enzymes such as Lys-C, trypsin, and proteinase K.
Their PCT Sample Preparation System is composed of various tools and consumables that the company has designed to complete the sample preparation processes in an efficient manner. One of the components is the Barocycler Intruments that comes in sizes. These way customers are able to choose the right one based on the requirements and preferences.
Pressure BioSciences, Inc. also offers consumables such as Pressure Used to Lyse Samples for Extraction, in short PULSE and other tubes. They are the conduit that transfers the power of the PCT from the Barocycler Instruments to the sample. The company also provides a PULSE tube tool that allows users to easily put the tube into place inside the Barocycler Instrument.
At present, the company has already installed more than 250 PCT systems in around 160 locations across the globe. The PCT platform has been proven to better than other similar methods.
Pressure BioSciences, Inc. provides a unique and efficient system, which is why a lot of laboratories worldwide prefer their PCT system than other sample preparation tools. By providing high–quality products since they were founded in 1978, Pressure Bio Science continues to grow year after year.
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